Peritoneal Dialysis (PD) is a type of dialysis used to remove waste products and excess fluid from the blood when the kidneys are not functioning properly (end-stage renal disease). It uses the lining of your abdomen (peritoneum) as a natural filter.
๐งฌ What is Peritoneal Dialysis?
⚙️ How It Works:
A sterile dialysis solution (dialysate) is introduced into the peritoneal cavity through a catheter. The peritoneal membrane acts as a semi-permeable barrier. Waste products and excess electrolytes from blood vessels in the peritoneum diffuse into the dialysate. After a set dwell time, the fluid (now containing waste) is drained out.
๐ Types of Peritoneal Dialysis:
1. Continuous Ambulatory Peritoneal Dialysis (CAPD)
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Manual exchange done 4–5 times a day
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Each exchange lasts 30–40 minutes
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No machine required
2. Automated Peritoneal Dialysis (APD) / Continuous Cycler-Assisted PD (CCPD)
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Machine (cycler) performs exchanges overnight while patient sleeps
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Typically 8–10 hours per night
๐ The PD Cycle:
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Fill – Dialysate is infused into the peritoneal cavity (~1.5 to 3 L)
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Dwell – Solution remains in the abdomen for several hours, allowing exchange of solutes
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Drain – Used solution is drained and replaced with fresh dialysate
๐ Catheter Placement:
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Done surgically (usually under local or general anesthesia)
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A Tenckhoff catheter is placed into the peritoneal cavity
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Heals over a few weeks before use
๐ Indications:
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Chronic Kidney Disease (CKD) Stage 5 / End-Stage Renal Disease (ESRD)
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Preference for home-based therapy
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Patients with vascular access issues (where hemodialysis is difficult)
❌ Contraindications:
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Extensive abdominal surgery/scarring
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Hernias
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Inflammatory bowel disease
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Severe obesity (relative)
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Lack of home support or patient compliance
๐ Advantages of PD:
❌ Disadvantages of PD:
⚠️ Common Complications:
1. Peritonitis – infection of the peritoneal cavity
2. Exit-site or tunnel infections
Redness, discharge, pain around the catheter site
3. Catheter malfunction
Obstruction or migration
4. Hernias or leaks due to increased intra-abdominal pressure
5. Dialysate-related issues
Glucose absorption → weight gain or hyperglycemia
๐งช Monitoring in PD:
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Weight and blood pressure daily
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Monthly labs: Electrolytes, urea, creatinine, hemoglobin, albumin
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Peritoneal Equilibration Test (PET): To assess membrane transport type
๐ PD vs Hemodialysis:
| Feature | PD | Hemodialysis |
|---|---|---|
| Location | Home | Dialysis center |
| Frequency | Daily | 3x/week |
| Access | Abdominal catheter | AV fistula/graft |
| Equipment | Minimal (or cycler) | Dialysis machine |
| Independence | High | Moderate |
| Risks | Peritonitis | Vascular access infections, hypotension |
๐ง⚕️ Training & Support:
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Patients and caregivers undergo training for 1–2 weeks
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Nurses teach sterile technique, exchange process, and troubleshooting
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Regular follow-up with nephrologist and dialysis nurse
๐ Lifestyle:
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Travel-friendly (portable supplies)
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Compatible with work/school life
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Diet more liberal than with hemodialysis (especially potassium and fluids)
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