A duodenal ulcer is a sore that forms on the lining of the duodenum, the first part of the small intestine. It is a type of peptic ulcer commonly caused by the H. pylori bacteria or long-term use of NSAIDs. Symptoms include a burning or dull pain in the abdomen, bloating, nausea, and feeling full, while treatments focus on eliminating the underlying cause and reducing stomach acid
A duodenal ulcer is a painful sore that develops on the inner lining of the duodenum, which is the first part of the small intestine — located just beyond the stomach. It is one of the most common types of peptic ulcers and can cause significant discomfort if not treated properly.
๐ What Causes a Duodenal Ulcer?
Most duodenal ulcers develop due to:
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Helicobacter pylori (H. pylori) infection – a spiral-shaped bacterium that weakens the protective mucous layer of the intestine, allowing stomach acid to cause damage.
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Long-term use of NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) – such as aspirin, ibuprofen, or naproxen, which can irritate the intestinal lining and increase acid production.
Other contributing factors may include stress, excessive alcohol consumption, and smoking, all of which can worsen the condition.
⚠️ Common Symptoms
People with duodenal ulcers often experience:
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A burning or dull pain in the upper abdomen, especially between meals or at night
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Bloating and nausea
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Feeling full quickly after eating
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Occasionally, symptoms like vomiting blood or black stools may indicate bleeding ulcers — requiring immediate medical attention.
๐ Treatment Options
Treatment for duodenal ulcers focuses on healing the sore and preventing recurrence:
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Antibiotics – to eliminate H. pylori infection
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Proton Pump Inhibitors (PPIs) or H2 blockers – to reduce stomach acid production
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Discontinuing NSAIDs – if they are the cause
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Lifestyle changes – such as eating balanced meals, avoiding spicy foods, quitting smoking, and limiting alcohol
๐ผ Final Thoughts
A duodenal ulcer is a manageable condition when detected early. With proper medical care, dietary changes, and medication, most patients recover fully and prevent future recurrences. Listening to your body and seeking early treatment can protect your digestive health for the long term.
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