Ileum cancer is a rare form of small intestine cancer that can cause symptoms like abdominal pain, nausea, and vomiting. Because the symptoms are often nonspecific, it can be difficult to diagnose, and it is sometimes only identified during surgery. The primary treatment is surgery to remove the tumor, with other therapies like chemotherapy or radiation considered depending on the specific situation.
Here’s your Ileum Cancer write-up expanded into a complete and blog-ready article, suitable for a medical or health blog, written in clear and informative language.
๐งฌ Ileum Cancer – Causes, Symptoms, Diagnosis & Treatment
By Dhurga
NOV 11, 2025 | 09:42 AM IST
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๐น Overview
Ileum cancer is a rare form of small intestine cancer that develops in the ileum, the last part of the small intestine connecting to the large intestine.
Although the small intestine makes up most of the digestive tract, cancers of the small intestine are uncommon, accounting for less than 3% of all gastrointestinal cancers.
Because symptoms are often vague or nonspecific, ileum cancer can be difficult to detect early and is sometimes diagnosed incidentally during surgery or imaging for another condition.
๐น Functions of the Ileum
The ileum plays a vital role in:
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Absorbing vitamin B12, bile salts, and nutrients from digested food.
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Acting as a bridge between the small and large intestines.
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Helping maintain a balanced gut flora and immune function.
When cancer develops in this region, these normal processes can be disrupted, leading to digestive and nutritional problems.
๐น Types of Ileum Cancer
Different types of tumors can arise in the ileum, including:
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Adenocarcinoma – The most common type, originating from the glandular cells of the intestinal lining.
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Carcinoid (Neuroendocrine) Tumors – Slow-growing tumors that may secrete hormones causing flushing or diarrhea.
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Lymphoma – Cancer of the lymphatic tissue in the intestine.
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Sarcoma (GIST – Gastrointestinal Stromal Tumor) – Arising from the smooth muscle or connective tissue cells.
๐น Causes & Risk Factors
The exact cause of ileum cancer is unknown, but several risk factors are associated with its development:
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Chronic inflammatory bowel disease (IBD), such as Crohn’s disease
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Genetic conditions like Familial Adenomatous Polyposis (FAP) or Lynch syndrome
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High-fat diet and smoked or processed food intake
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Age – More common in people over 60 years
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Smoking and alcohol use
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Long-standing infections or radiation exposure
๐น Common Symptoms
Symptoms of ileum cancer are often nonspecific and can mimic other digestive disorders such as ulcers or irritable bowel syndrome.
Typical signs may include:
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Persistent abdominal pain or cramping
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Nausea and vomiting
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Bloating or feeling of fullness
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Unexplained weight loss
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Fatigue or weakness
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Blood in stool or black/tarry stools (melena)
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In advanced stages: bowel obstruction or intestinal perforation
๐น Diagnosis
Because the ileum is located deep within the abdomen, diagnosis often requires specialized tests.
Common diagnostic methods include:
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CT scan or MRI – To visualize tumors and check for spread.
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Endoscopy or Enteroscopy – To look directly inside the small intestine.
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Capsule Endoscopy – Swallowing a camera pill that takes thousands of pictures.
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Biopsy – Sampling tissue for microscopic examination.
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Blood tests – To check for anemia or tumor markers.
In many cases, ileum cancer is only discovered during surgery for suspected obstruction or other abdominal issues.
๐น Treatment Options
The primary treatment for ileum cancer is surgical removal of the tumor and surrounding tissue.
1. Surgery
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Segmental resection: Removal of the affected part of the ileum with nearby lymph nodes.
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Bypass surgery may be done in cases where the tumor cannot be completely removed.
2. Chemotherapy
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Used before or after surgery, depending on the cancer type and stage.
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Commonly used drugs: 5-Fluorouracil (5-FU), Capecitabine, or Oxaliplatin.
3. Radiation Therapy
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Used less frequently but may help relieve pain or control local tumor growth.
4. Targeted Therapy / Immunotherapy
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For advanced cases, drugs targeting specific mutations or immune pathways may be considered.
๐น Prognosis
The outlook (prognosis) depends on:
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The type and stage of cancer at diagnosis
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Whether the tumor has spread (metastasized)
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The patient’s overall health and response to treatment
Early-stage ileum cancers have a much better survival rate when surgically removed completely.
Late diagnosis, however, can reduce treatment success due to metastasis to the liver or lymph nodes.
๐น Prevention & Early Detection Tips
While ileum cancer cannot always be prevented, these steps may reduce the risk:
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Maintain a healthy diet rich in fruits, vegetables, and fiber.
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Avoid smoking and excessive alcohol use.
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Treat inflammatory bowel conditions promptly.
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Undergo regular check-ups if you have a family history of intestinal cancers.
๐น Summary Table
| Aspect | Details |
|---|---|
| Location | Ileum (last part of small intestine) |
| Cancer type | Adenocarcinoma, Carcinoid, Lymphoma, GIST |
| Main symptoms | Abdominal pain, nausea, vomiting, obstruction |
| Diagnosis | CT/MRI, Endoscopy, Biopsy |
| Treatment | Surgery, Chemotherapy, Radiation |
| Prognosis | Better if detected early |
๐ฉบ Conclusion
Ileum cancer is rare but serious. Because symptoms often resemble common digestive problems, early diagnosis is challenging.
Awareness of the warning signs and timely medical evaluation can help detect the disease earlier and improve outcomes.
Surgery remains the cornerstone of treatment, often followed by chemotherapy or radiation depending on the stage.
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